The Effects of Leptin Replacement on Neural Plasticity

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The Effects of Leptin Replacement on Neural Plasticity

Leptin, an adipokine synthesized and secreted mainly by the adipose tissue, has multiple effects on the regulation of food intake, energy expenditure, and metabolism. Its recently-approved analogue, metreleptin, has been evaluated in clinical trials for the treatment of patients with leptin deficiency due to mutations in the leptin gene, lipodystrophy syndromes, and hypothalamic amenorrhea. In ...

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ژورنال

عنوان ژورنال: Neural Plasticity

سال: 2016

ISSN: 2090-5904,1687-5443

DOI: 10.1155/2016/8528934